한국임상수의학회지 (Journal of Veterinary Clinics)

  • 제18권1호
  • /
  • Pages.29-34
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  • 2001
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  • 1598-298X(pISSN)
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  • 2384-0749(eISSN)
한국임상수의학회 (The Korean Society of Veterinary Clinics)
권호 표지

개에 있어서 Xylazine 진정에 대한 Atipamezole의 길항효과

Antagonistic Effects of Atipamezole on Xylazine Induced Sedation in Dogs

  • 김휘율 (건국대학교 수의과대학 수의외과학교실) ;
  • 임희란 (건국대학교 수의과대학 수의외과학교실) ;
  • ;
  • ;
  • 발행 : 2001.03.01
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초록

Antagonistic effects of atipamezole(50, 100, 200, 400 $\mu\textrm{g}$/kg, i.m.) on sedation induced with xylazine (2 mg/kg, i.m.) were evaluated in dogs. Atipamezole at doses of 100~400$\mu\textrm{g}$/kg effectively reversed sedation, and the arousal time, standing time and total recovery time were significantly shortened. The optimal action of atipamezole was seen at a dose of 100 $\mu\textrm{g}$/kg. At this dose recovery from sedation was quick and smooth, and adverse effects such as hyperactivity or tachycardia were minimal with or without atropine premedication.

키워드

참고문헌

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