Journal of Veterinary Clinics (한국임상수의학회지)

The Korean Society of Veterinary Clinics (한국임상수의학회)
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Antagonistic Effects of Atipamezole on Xylazine Induced Sedation in Dogs

개에 있어서 Xylazine 진정에 대한 Atipamezole의 길항효과

  • 김휘율 (건국대학교 수의과대학 수의외과학교실) ;
  • 임희란 (건국대학교 수의과대학 수의외과학교실) ;
  • ;
  • ;
  • Published : 2001.03.01
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Abstract

Antagonistic effects of atipamezole(50, 100, 200, 400 $\mu\textrm{g}$/kg, i.m.) on sedation induced with xylazine (2 mg/kg, i.m.) were evaluated in dogs. Atipamezole at doses of 100~400$\mu\textrm{g}$/kg effectively reversed sedation, and the arousal time, standing time and total recovery time were significantly shortened. The optimal action of atipamezole was seen at a dose of 100 $\mu\textrm{g}$/kg. At this dose recovery from sedation was quick and smooth, and adverse effects such as hyperactivity or tachycardia were minimal with or without atropine premedication.

Keywords

References

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