대한한방내과학회지 (The Journal of Internal Korean Medicine)

대한한방내과학회 (The Society of Internal Korean Medicine)
권호 표지

소건중탕가룡골(小建中湯加龍骨).모려(牡蠣)가 흰쥐의 실험적 위궤양에 미치는 영향

The Effects of Shogunjungtang-ga-yonggol.morea on Gastric Ulcer

  • 김태중 (경산대학교 한의과대학 내과학교실) ;
  • 이윤희 (경산대학교 한의과대학 내과학교실) ;
  • 최우석 (경산대학교 한의과대학 내과학교실) ;
  • 박순달 (경산대학교 한의과대학 내과학교실) ;
  • 변준석 (경산대학교 한의과대학 내과학교실)
  • Kim, Tae-Joong (Department of internal Medicine, College of Oriental Medicine, Kyungsan University) ;
  • Lee, Yun-Hee (Department of internal Medicine, College of Oriental Medicine, Kyungsan University) ;
  • Choi, Woo-Seok (Department of internal Medicine, College of Oriental Medicine, Kyungsan University) ;
  • Park, Soon-Dal (Department of internal Medicine, College of Oriental Medicine, Kyungsan University) ;
  • Byun, Joon-Seok (Department of internal Medicine, College of Oriental Medicine, Kyungsan University)
  • 발행 : 2001.03.30
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초록

Object : This study was carried out to examine the effects of Shogunjungtang-ga-younggol morea on gastric ulcers. Methods : In order to study the effects of Shogunjungtang-ga-younggol morea on gastric ulcers. Gastric ulcers were induced in HCI-aspirin in rats. The experiments were done by oral administration and measured by anatohistological features of ulcer lesions, and the changes of the number of parietal cells, chief cells, gastrin and somatostatin- immunoreactive cells. Results : In the Shogunjungtang-ga-younggol morea administrated groups, no gross lesions of ulcer and anatohistologically, just minor injury of gastric mucosa were detected. The number of parietal cells were significantly decreased, and the number of chief cells were significantly increased, in administrated groups. The number of gastrin-immunoreactive cells and somatostatin-immunoreactive cells was significantly increased in administrated groups. Conclusion : According to the results, it is considered that the administration of Shogunjungtang-ga-younggol morea seems to be applicable to the treatment of gastric ulcers.

키워드

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