Journal of the Korean Association of Oral and Maxillofacial Surgeons
- 제27권5호
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- Pages.468-473
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- 2001
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- 2234-7550(pISSN)
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- 2234-5930(eISSN)
악안면 영역의 Castleman's disease의 치험례
A CASE REPORT OF CASTLEMAN'S DISEASE ON ORAL AND MAXILLOFACIAL REGION
- 정인교 (부산대학교 치과대학 구강악안면외과학교실) ;
- 김욱규 (부산대학교 치과대학 구강악안면외과학교실) ;
-
신상훈
(부산대학교 치과대학 구강악안면외과학교실) ;
-
박혜련
(부산대학교 치과대학 구강병리학교실) ;
- 이의훈 (부산대학교 치과대학 구강악안면외과학교실) ;
- 장원석 (부산대학교 치과대학 구강악안면외과학교실)
- Chung, In-Kyo (Department of Oral and Maxillofacial surgery, College of Dentistry, Pusan National University) ;
- Kim, Uk-Kyu (Department of Oral and Maxillofacial surgery, College of Dentistry, Pusan National University) ;
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Shin, Sang-Hoon
(Department of Oral and Maxillofacial surgery, College of Dentistry, Pusan National University) ;
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Park, Hye-Ryun
(Department of Oral pathology, College of Dentistry, Pusan National University) ;
- Lee, Eui-Hoon (Department of Oral and Maxillofacial surgery, College of Dentistry, Pusan National University) ;
- Jang, Won-Seok (Department of Oral and Maxillofacial surgery, College of Dentistry, Pusan National University)
- 발행 : 2001.10.30
초록
본 교실에서는 우측 악하부와 우측 안와 하부의 종창으로 내원한 53세 여자 환자에서 Fine Needle Aspiration Biopsy로 림프절의 반응성 과증식으로 진단되어 다시 절제 생검을 시행하여 multi-centric Castleman's disease로 진단하였다. 조직 검사상 유리질 혈관형과 형질세포형이 공존하는 복합형으로 나타났으며 병소의 적출술만을 시행한 후 1년이 지난 지금까지는 별다른 소견없이 좋은 경과를 나타내고 있으며 앞으로도 계속 주의깊은 관찰이 필요로 한다.
Castleman's disease or angiofollicular lymph node hyperplasia, is a rare lymphoproliferative disorder. It may be appear as a local or generalized tumor-like condition, usually in chest or abdomen and may involve both lymph nodes and non-nodal tissues. Castleman's disease is an unusal entity which may at times mimic malignancy but is entirely benign in nature. It is topical as it has been noted to occur with AIDS and Kaposi's sarcoma. Careful interpretation of radiogram may help to distinguish Castleman's disease from other tumor condition, such as lymphoma, neurogenic tumor, or even angiofibroma, etc. But exact diagnosis must be made on the basis of histologic confirmation. In addition to histologic features, clinical distinction between the localized and multicentric form is important in selecting appropriate management. Surgical excision of an localized mass is the first choice of treatment. Partial resection, radiotherapy or observation alone may avoid the need for exessively aggressive therapy. Patients with multicentric disease don't benefit by surgical management because of systemic manifestation and rapid deterioration. Thus, antineoplastic agents and steroids may offer an alternative form of therapy. We report a case of female patient with Castleman's disease in oral and maxillofacial region, treated by surgical excision with good results.