Korean Journal of Pharmacognosy (생약학회지)
- Volume 32 Issue 3 Serial No. 126
- /
- Pages.189-192
- /
- 2001
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- 0253-3073(pISSN)
- /
- 2288-9299(eISSN)
Cytotoxicity and Quantitative Analysis of Nortriterpenoid glycoside from Scilla scilloides
무릇에서 분리한 nortriterpenoid glycoside의 암세포에 대한 세포독성 및 함량 분석
- Lee, Sang-Myung (Korea Research Institute of Bioscience and Biotechnology) ;
-
Chun, Hyo-Kon
(Korea Research Institute of Bioscience and Biotechnology)
;
-
Lee, Choong-Hwan
(Korea Research Institute of Bioscience and Biotechnology)
;
- Lee, Ho-Jae (Korea Research Institute of Bioscience and Biotechnology) ;
- Kang, Shin-Jyung (Department of Life Science, Joongbu University) ;
- Maeng, Hack-Young (Department of Life Science, Joongbu University) ;
- Kho, Yung-Hee (Korea Research Institute of Bioscience and Biotechnology)
- 이상명 (한국생명공학연구원) ;
-
전효곤
(한국생명공학연구원)
;
-
이충환
(한국생명공학연구원)
;
- 이호재 (한국생명공학연구원) ;
- 강진정 (중부대학교 생명자원학부) ;
- 맹학영 (중부대학교 생명자원학부) ;
- 고영희 (한국생명공학연구원)
- Published : 2001.09.30
Abstract
Scillascilloside E-3 (1) and E-1 (2) were isolated from the bulbs of Scilla scilloides. The cytotoxic activities of these compounds were tested against murine (B16/F-10, 3LL) and human cancer cell lines (MCF7, PC-3, HT29, LOX-IMVI, A549 and HT1080). These compounds exhibited a significant cytotoxic activities against all tested cancer cells. Futhermore, the contents of 1 and 2 in S. scilloides are 43.2 and 27.9 mg/kg, respectively.