Natural Product Sciences
- Volume 7 Issue 3
- /
- Pages.87-89
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- 2001
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- 1226-3907(pISSN)
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- 2288-9027(eISSN)
Gastroprotective Activity of the Unripe Fruit Extract of Juglans mandshurica in Rats
-
Lee, Eun-Bang
(Natural Products Research Institute, Seoul National University)
;
- Hyun, Jin-Ee (Natural Products Research Institute, Seoul National University) ;
- Li, Da-Wei (Natural Products Research Institute, Seoul National University) ;
-
Jeong, Choon-Sik
(College of Pharmacy, Duksung Women's University)
;
-
Shin, Seung-Won
(College of Pharmacy, Duksung Women's University)
;
- Cho, Sung-Ig (Dept. of Pharmacology, Ajou University School of Medicine) ;
-
Jhon, Gil-Ja
(College of Natural Sciences, Ewha Womans University)
;
- Lee, Eun-Hee (College of Natural Sciences, Ewha Womans University)
- Published : 2001.09.01
Abstract
The unripe fruit extract of Juglans mandshurica showed significant inhibition on aspirin and indomethacin induced gastric lesion at an oral dose of 1000 mg/kg. The extract did not show inhibition of aspirin induced ulcer and Shay ulcer at the doses of 500 and 1000 mg/kg. The results indicate that the extract had a gastroprotective activity.