Tiliacosine and Tiliasine, two New Bisbenzylisoquinoline Alkaloids from Tiliacora racemosa

  • Seal, Tapan (Botanical Survey of India, Indian Botanic Garden) ;
  • Patra, Amarendra (Centre of Advanced Studies on Natural Products, Department of Pure Chemistry, University College of Science) ;
  • Mukhopadhayay, Gobinda (S. N. Pradhan Centre for Neurosciences, B. C. Roy Post Graduate Institute of Basic Medical Sciences) ;
  • Mukherjee, Biswapati (S. N. Pradhan Centre for Neurosciences, B. C. Roy Post Graduate Institute of Basic Medical Sciences)
  • Published : 2001.09.01

Abstract

Two new bisbenzylisoquinoline alkaloids tiliacosine (1) and tiliasine (2) were isolated from the leaves of Tiliacora racemosa Colebr.. The structures of these alkaloids were established on the basis of spectral evidence and by the correlation of their $^1H-NMR$ spectral data with those of the congeners N-methyltiliamosine (3), tiliamosine (4) and tiliacorine (5).

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