Malignant Neurocutaneous Melanosis - A Case Report -

악성 신경피부흑색증 - 증례보고-

  • Kim, Tae Young (Department of Neurosurgery, School of Medicine, Wonkwang University) ;
  • Oh, Kwang Soo (Department of Pediatrics, School of Medicine, Wonkwang University) ;
  • Lee, Young Jin (Department of Clinical Pathology, School of Medicine, Wonkwang University) ;
  • Yun, Ki Jung (Department of Pathology, School of Medicine, Wonkwang University) ;
  • Kim, Jong Moon (Department of Neurosurgery, School of Medicine, Wonkwang University)
  • 김태영 (원광대학교 의과대학 신경외과학교실) ;
  • 오광수 (원광대학교 의과대학 소아과학교실) ;
  • 이영진 (원광대학교 의과대학 임상병리학교실) ;
  • 윤기중 (원광대학교 의과대학 병리학교실) ;
  • 김종문 (원광대학교 의과대학 신경외과학교실)
  • Received : 1999.04.27
  • Accepted : 1999.11.10
  • Published : 2000.03.28

Abstract

Arare case of primary malignant melanoma of central nervous system in 12-month-old infant with neuro-cutaneous melanosis is presented. Primary malignant melanomas in central nervous system are very rare in children, however, it is known that leptomeningeal melanosis is malignant in 40-50% with neurocutaneous melanosis. Spinal MRI, brain CT and MRI showed diffuse intradural extramedullary mass of entire spinal cord and enhancing mass in brain stem. CSF cytology revealed abnormal cells. Biopsy from leptomeninges of posterior fossa was compatible with malignant melanoma.

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