Enterobacter Aerogenes에 의한 뇌실염에 대한 Pefloxacine의 뇌실내 주입 - 증 례 보 고 -

Intraventricular Pefloxacine Therapy for a Cerebral Ventriculitis by Enterobacter Aerogenes - Case Report -

A 40-year-old female with hypertensive thalamic hemorrhage, secondary intraventricular hemorrhage, and hydrocephalus was treated with extraventricular drainage. She developed catheter-related ventriculitis caused by gram-negative rods, Enterobacter aerogenes. She was treated with systemic pefloxacine, ceftazidime, amikin and intraventricular vancomycin, gentamicin was unsuccessful. The ventriculitis was successfully controlled by intraventricular administration of the pefloxacine. Regarding their excellent activity against gram-negative rods, Enterobacter aerogenes, and probable safety when administered intraventricularly, administration of the pefloxacine, may be considered in the treatment of ventriculitis if the pathogen is resistant to other conventional antibiotics.