Journal of Oral Medicine and Pain

Korean Academy of Orofacial Pain and Oral Medicine (대한안면통증구강내과학회)
권호 표지

Genetic Variations of D16S539 Locus in the Korean Population

한국인에서 D16S539 유전좌의 유전적 다형성

  • Shin, Kyoung-Jin (Department of Forensic Medicine, College of Medicine, Yonsei University) ;
  • Yang, Yun-Seok (Department of Forensic Medicine, College of Medicine, Yonsei University) ;
  • Choi, Jong-Hoon (Department of Oral Medicine, College of Dentistry, Yonsei University) ;
  • Yang, Woo-Ick (Department of Forensic Medicine, College of Medicine, Yonsei University) ;
  • Cho, Sang-Ho (Department of Forensic Medicine, College of Medicine, Yonsei University) ;
  • Kim, Chong-Youl (Department of Oral Medicine, College of Dentistry, Yonsei University)
  • 신경진 (연세대학교 의과대학 법의학과) ;
  • 양윤석 (연세대학교 의과대학 법의학과) ;
  • 최종훈 (연세대학교 치과대학 구강내과학교실) ;
  • 양우익 (연세대학교 의과대학 법의학과) ;
  • 조상호 (연세대학교 의과대학 법의학과) ;
  • 김종열 (연세대학교 치과대학 구강내과학교실)
  • Published : 2000.12.30
Download PDF
⟨ Previous Next ⟩

Abstract

The D165539 locus was investigated to collect population genetic data in the Korean population. The selected subject was unrelated 293 Korean people. DNA was extracted from the samples and PCR was performed with fluorescent primer. The amplified fragment was analysed by automated DNA sequencer and it's application software. Among the Korean population, 7 allele and 18 geneotype were observed and allele No. 9 is mostly frequent(0.2679) and then allele No. 11(0.2679), allele No. 9(0.2645). The observed heterozygosity and the expected heterozygosity is 0.7466, 0.7829 each. The polymorphism information content(PIC) is 0.7466. The power of discrimination(PD) and the mean exclusion chance(MEC) are calculated to be 0.9190 and 0.5775.

Keywords