Maxillofacial Plastic and Reconstructive Surgery

Korean Association of Maxillofacial Plastic and Reconstructive Surgeons (대한악안면성형재건외과학회)
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Effect of Methylprednisolone on the Healing Process after $Medpor^{(R)}$ Implantation in Rats

Medpor 매식후 치유과정에서 Methylprednisolone이 미치는 영향

  • Kim, Su-Gwan (Department of Oral and Maxillofacial Surgery, Oral Biology Research Institute College of Dentistry, Chosun University) ;
  • Chung, Sung-Su (Department of Anesthesiology, College of Dentistry, Chonnam University)
  • 김수관 (조선대학교 치과대학 구강악안면외과학교실, 구강생물학연구소) ;
  • 정성수 (전남대학교 치과대학 마취학교실)
  • Published : 2000.06.30
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Abstract

The purpose of this study is to evaluate the difference in healing of $Medpor^{(R)}$ implants of two different thickness (1.5mm and 4.5mm) and the effects of methylprednisolone on the healing process. Light microscopic and scanning electron microscopic examinations, and hardness measurement were made in 100 rats 2, 4, or 8 weeks postoperatively. The 1.5mm thin implants were taken better than the 4.5mm thick implants. The inflammatory responses were reduced after application of methylprednisolone with arrangement and amount of bone matrix deposited being more irregular and reduced in bulk than in the control group. To hasten postoperative healing after $Medpor^{(R)}$ implantation, the thinner material should be used and steroid injection should be avoided.

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