American Pit Bull Terrier메서 파상풍에 대한 임상적 및 미생물학적인 진단

Clinical and Microbiological Diagnosis of Tetanus in an American Pit Bull Terrier dog

  • 허은정 (전북대학교 생체안전성연구소) ;
  • 박영재 (박영재 동물병원) ;
  • 김남수 (전북대학교 생체안전성연구소) ;
  • 송희종 (전북대학교 생체안전성연구소) ;
  • 채준석 (전북대학교 생체안전성연구소)
  • 발행 : 2000.12.01

초록

A 3 year-old male American Pit Bull Terrier in Kwang-Ju, Chonnam was admitted to the Teaching Animal Hospital, Chonbuk National University. He showed convulsive spasms of skeletal muscles, raised tail-head, and rigidity of rigidity. Based on these clinical sign\ulcorner tetanus was suspected Hematological test results showed and WBC value (21 ,800/$\mu$l/) with neutrophils (17.877/$\mu$l) and monocytes (1.744/$\mu$l). The blood chemical values ALT (86 IU/L) and AST (119 IU/L) were elevated. Fecal sample from the dog was cultured in anaerobic chamber. A Gram positive, drumstick shaped bacteria was isolated. The bacteria was identified as Clostridium tetani by biological and biochemical tests. The dog was hospitalized in a quiet place where the light was cut off and treated with penicillin G procaine and phenobarbital sodium. The dog made a complete recovery 25 days after treatment. This Is the first report on C. tetani infection of domestic dog in Korea.

키워드

참고문헌

  1. Br Med J. v.291 Treatment of tctanus:an open study to compare the efficacy of procaine penicillin and metronidazole Ahmadsyah I;Salim A
  2. Naunyn Schmiedebergs Arch Pharmacol v.316 Tetanus toxin and botulinum A toxin inhibit acetylcholine release from but not calcium uptake into brain tissue Bigalke H;Ahnert-Hilger G;Habermall E
  3. Jpn Exp Med v.58 Some factors affecting isolation of Clostridium tetani from human and animal stools Ebisawa I;Takayanagi M;Kigawa M
  4. Nucl Acid Res v.14 The complete mucleotide sequence of tetanus toxin Fairweather NF;Lyness VA
  5. J Clin Microbiol v.32 Detection of type A.B. and botulism neurotoxin gene in Clostridium botulinum and other Clostridium species PCR:evidence of unexpressed type B toxin genes in type A toxigenic organism Franciosa G;Ferreira JL;Hatheway CL
  6. J Vet Intern Med v.8 Tetanus in the horse: a review of 20 cases (1970 to 1990) Green SL;Little CB;Baird JD;Tremblay RR;Smith-Maxie LL
  7. Color atlas and textbook of diagnostic microbiology (3rd ed) Koneman EW;Allen SD;Dowell VR;Janda WM;Sommers HM;Winn WC Jr
  8. Chem Res Toxicol v.13 Identification of novel small molecule ligands that bind to tetanus toxin Lightstone FC;Prieto MC;Singh AK;Piqueras MC;Whittal RM;Knapp MS;Balhorn R;Roe DC
  9. Prim Care Update Ob/Gyns v.4 Dignosis, treatment, and prevention of tetanus Million A
  10. A human perspective microbiology Nester EW;Roberts CE;Nester MT
  11. J Emerg Med v.16 Case report of an unusual source of tetanus Shelton D;Penciner R
  12. Genus Clostridium.In: Bergey's manual of systematic bacteriology Sneath PHA;Mair NS;Shape ME;Holt JG
  13. The genus Clostridium.In:Hagan and Bruner's microbiology and infectious disease of domestic animals (8th ed) Timoney JF;Gillespie JH;Scott FW;Barlough JE
  14. 破傷風.In:圭要症狀を基礎にしに 犬の臨床 其田三夫(監修)