KSBB Journal

The Korean Society for Biotechnology and Bioengineering (한국생물공학회)
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Isolation and Identification of 13-Deacetyl-taxchinin I, a New Taxoid from Plant Cell Cultures of Taxus chinensis

식물세포 Taxus chinensis 배양으로부터 신물질 13-Deacetyl-taxchinin I의 분리 및 동정

  • 김진현 ((주)삼양제넥스 생명공학연구소) ;
  • 기은숙 ((주)삼양제넥스 생명공학연구소) ;
  • 유시용 (한국화학연구소) ;
  • 최형균 ((주)삼양제넥스 생명공학연구소) ;
  • 홍승서 ((주)삼양제넥스 생명공학연구소) ;
  • 이현수 ((주)삼양제넥스 생명공학연구소)
  • Published : 2000.12.01
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Abstract

13-Deacetyl-taxchinin I, a taxoid having a rearranged 11(15\longrightarrow1)-abeo-taxane skeleton, has been isolated and identified from plant cell cultures of Taxus chinensis. The compound has not previously been encountered in nature. Its structure was elucidated by 1-and 2D NMR techniques including H-H COSY, HMQC, and HMBC experiments. This taxoid also provides information for better understanding of structure-activity relationships and biosynthesis, as well as improving the quality control of paclitaxel production.

Keywords

References

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