Journal of Veterinary Clinics (한국임상수의학회지)

The Korean Society of Veterinary Clinics (한국임상수의학회)
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Effect of Propolis on Healing of Full-thickness Skin Wound in Rabbits

Propolis가 토끼의 전층 피부 창상치유에 미치는 영향

  • 정성일 (충북대학교 수의과대학 및 동물의학연구소) ;
  • 강성수 (충북대학교 수의과대학 및 동물의학연구소) ;
  • 조성구 (충북대학교 농과대학) ;
  • 정석화 (충북대학교 수의과대학 및 동물의학연구소)
  • Published : 2000.06.01
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Abstract

The effects of vaselin, silver sulfadiazine and propolis on healing of full-thickness skin defects were evaluated in rabbits. Two wounds measuring 2{times}2cm$ were created bilaterally (4 wounds/rabbit) on the dorsolateral aspect of the trunk of 17 Ne Zealand white. Wound treatments were evenly distributed 4 sites, using a Latin square design. Treatments evaluated were: vaselin(group A), silver sulfadiazine(group B), 5% propolis (group C) and 10% propolis(group D). On days 3, 7 and 14, mean percentage of wound in group A, B, and C. On days 21 and 28, mean percentage of wound contraction in group D were significantly higher than those of groups B and C, but were not higher than that of group A. Microscopically fibersis and epithelialization were noticed on days 14 and 28 after wounding in all group. Rates of fibrosis of collagen fiber and epithelialization of groups C and D were exceeded those of groups A and B. All wounds in all group achieved 100% healing during the 28-day study period. Results indicate that use of propolis as would ointment on full-thickness skin wounds in rabbits increase rate of healing.

Keywords

References

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