Studies on the Hemolytic Activities of Korean Wild Mushrooms (II) - Screening of 22 Mushrooms Including Laccaria vinaceoavellanea for Their Hemolytic Activities -

한국산 야생버섯의 용혈작용에 대한 연구 -제 2보: 색시졸각버섯(Laccaria vinaceoavellanea)등 22종의 in vitro 용혈활성 검색 -

  • Chung, Kyeong-Soo (College of Pharmacy, Chungnam National University) ;
  • Lee, Ji-Seon (College of Pharmacy, Chungnam National University) ;
  • Jo, Moon-Joo (College of Pharmacy, Chungnam National University) ;
  • Lee, Im-Seon (College of Pharmacy, Chungnam National University)
  • Published : 2000.10.30

Abstract

To investigate the hemolytic toxicities of the Korean basidiomycetes, the cold-water extracts of 22 wild mushrooms were tested for their hemolytic activities on the erythrocytes of a mouse and a rat. As a result, three species including Collybia confluence, Laccaria vinaceoavellanea and Lenzites betulina showed strong hemolytic activities. Of these, L. vinaceoavellanea retained more than 80% of its hemolytic activity even after it was boiled for 30 minutes, while the other two were inactivited in five minutes.

한국산 야생버섯 22종의 용혈독성을 규명하기 위하여 그 냉침액(cold water extract)의 용혈활성을 검색하여 다음과 같은 결과를 얻었다. 1. Collybia confluence(밀버섯), Laccaris vinaceoavellanea(색시졸각버섯) 및 Lenzites betulina(조개껍질버섯) 등 3 종이 mouse 및 rat 적혈구에 대하여 강력한 용혈 작용을 나타내었다. 2. L. vinaceoavellanea은 $100^{\circ}C$ 수욕상에서 30분간 가열하여도 mouse 적혈구에 대한 용혈활성이 80% 이상 유지되어, 열에 매우 안정한 용혈성분을 함유하는 것으로 확인되었다.

Keywords

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