The Journal of Internal Korean Medicine (대한한방내과학회지)

The Society of Internal Korean Medicine (대한한방내과학회)
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Study on Antitumor Effects of Sambonggangyongbaneo-tang and Gagamsojeokbaekchoo-san

삼봉강룡반어탕(三蓬薑龍半魚湯)과 가감소적백출산(加減消積白朮散)의 항암효과(抗癌效果)에 대(對)한 비교연구(比較硏究)

  • Kim, Dong-Woo (Dept. of Internal Medicine, College of Oriental Medicine, Kyung-Won University) ;
  • Ko, Seung-Hi (Dept. of Internal Medicine, College of Oriental Medicine, Kyung-Won University) ;
  • Choi, You-Kyung (Dept. of Internal Medicine, College of Oriental Medicine, Kyung-Won University) ;
  • Shim, Mun-Ki (Dept. of Internal Medicine, College of Oriental Medicine, Kyung-Won University) ;
  • Yeo, Eun-Kyung (Dept. of Internal Medicine, College of Oriental Medicine, Kyung-Won University) ;
  • Park, Se-Ki (Dept. of Internal Medicine, College of Oriental Medicine, Kyung-Won University) ;
  • Park, Chong-Hyeong (Dept. of Internal Medicine, College of Oriental Medicine, Kyung-Won University) ;
  • Ko, Jae-Chul (Kyung-Won University Inchun Medical Center) ;
  • Jun, Chan-Yong (Kyung-Won University Inchun Medical Center) ;
  • Han, Yang-Hee (Dept. of Internal Medicine, College of Oriental Medicine, Kyung-Won University) ;
  • Lee, Chung-Jung-Hye (Dept. of Internal Medicine, College of Oriental Medicine, Kyung-Won University)
  • 김동우 (경원대학교 한의과대학 내과학교실) ;
  • 고승희 (경원대학교 한의과대학 내과학교실) ;
  • 최유경 (경원대학교 한의과대학 내과학교실) ;
  • 심문기 (경원대학교 한의과대학 내과학교실) ;
  • 여은경 (경원대학교 한의과대학 내과학교실) ;
  • 박세기 (경원대학교 한의과대학 내과학교실) ;
  • 박종형 (경원대학교 한의과대학 내과학교실) ;
  • 고재철 (경원대학교 인천 한방병원 내과) ;
  • 전찬용 (경원대학교 인천 한방병원 내과) ;
  • 한양희 (경원대학교 한의과대학 내과학교실) ;
  • 이청정혜 (경원대학교 한의과대학 내과학교실)
  • Published : 2000.11.30
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Abstract

Objective : It is well known that Gagamsojeokbackchool-san show antitumor effects and its activities are result from enhancement of immune function, we investigated the antitumor effects of Sambonggangyongbaneo-tang and its mechanism. Methods : We measured change of body weight, weight of immune organs (Spleen, Thymus), Liver, Kidney, tumor weight, cytotoxicity for investigation of antitumor effects of Sambonggangyongbaneo-tang. Results : 1. The body weight of mouse has no significant difference between control and sample groups. 2. The weights of immune organs (Spleen and Thymus) decreased significantly in sample groups. The weights of Liver and Kidney have no significant difference. 3. The tumor weights in mouse decreased significantly in sample groups and showed dose-dependent effect. 4. Cell viability of Sarcoma 180 has no significant difference in sample groups. 5. HeLa cell viability has no significant difference in low concentration, but it decreased significantly in high concentration. Conclusions : According to the above results, it could be suggested that Sambonggangyongbaneo-tang has prominant antitumor effects and cytotoxicity.

Keywords

References

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