Korean Journal of Oriental Medicine (한국한의학연구원논문집)

Korean Institute of Oriental Medicine (한국한의학연구원)
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Inhibitory Effects of Chungpesagan-Tang on Ischemia/Reperfusion-Induced Inflammatory Responses In vitro

허혈/재관류 환경하에서 청폐사간탕의 염증 관련 반응 억제 효과

  • Hong, Seong-Gil (Department of Medical Research & Development, Korea Institute of Oriental Medicine) ;
  • Kang, Bong-Joo (Department of Medical Research & Development, Korea Institute of Oriental Medicine) ;
  • Cho, Dong-Wuk (Department of Medical Research & Development, Korea Institute of Oriental Medicine)
  • 홍성길 (한국한의학연구원 의료연구부) ;
  • 강봉주 (한국한의학연구원 의료연구부) ;
  • 조동욱 (한국한의학연구원 의료연구부)
  • Published : 2000.04.30
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Abstract

Chungpesagan-Tang (CST), a Korean traditional prescription composed of oriental medical herbs, has been used successfully to improve human health and regimen. This study was designed to examine the inhibitory effects of CST against in vitro ischemia/reperfusion-induced inflammatory response. We have characterized the production of prostaglandin $E_2$ and arachidonic acid during ischemia/reperfusion in the human neuroblastoma SK-N-MC and human monocytic macrophage U937 cells and the inhibitory effect of CST on these inflammation-related substance formation has been found out in this study. This result suggested that CST used in this experiment reinforced antiinflammatory potentials and protected cells against ischemia/reperfusion-induced inflammatory resopnse.

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