Natural Product Sciences

The Korean Society of Pharmacognosy (한국생약학회)
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Phenolic Compounds from Orostachys japonicus having Anti-HIV-1 Protease Activity

  • Park, Ju-Gwon (Department of Oriental Medicine Resources, Sunchon National University) ;
  • Park, Jong-Cheol (Department of Oriental Medicine Resources, Sunchon National University) ;
  • Hur, Jong-Moon (Department of Oriental Medicine Resources, Sunchon National University) ;
  • Park, Sung-Jong (Department of Oriental Medicine Resources, Sunchon National University) ;
  • Choi, Da-Rae (Department of Oriental Medicine Resources, Sunchon National University) ;
  • Shin, Dong-Young (Department of Plant Resources, Sunchon National University) ;
  • Park, Ky-Young (Department of Biology, Sunchon National University) ;
  • Cho, Hyun-Wook (Department of Biology, Sunchon National University) ;
  • Kim, Moon-Sung (Dong-A Pharm. Co.)
  • Published : 2000.09.01
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Abstract

The water extract of the aerial parts of Orostachys japonicus A. Berger showed the inhibitory activity against HIV-1 protease. From the same parts of O. Japanicus, 4-hydroxybenzoic acid, 3,4-dihydroxybenzoic acid, gallic acid and methyl gallate, together with flavonoids, kaempferol, quercetin, kaempferol $3-O-{\beta}-D-glucoside$, kaempferol $3-O-{\beta}-D-galactoside$ and quercetin $3-O-{\beta}-D-glucoside$ were isolated and characterized by spectral data.

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