Natural Product Sciences

The Korean Society of Pharmacognosy (한국생약학회)
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Bioactive Carotenoid, Fucoxanthin as Chemotaxonomic Marker and Antioxidative Agent from the Marine Bacillariophycean Microalga Hantzschia marina

  • Choi, Jin-Seok (Department of Chemistry, Pukyong National University,Department of Food Science and Technology, Kyungsung University) ;
  • Lee, Won-Kap (Department of Chemistry, Pukyong National University,Department of Food Science and Technology, Kyungsung University) ;
  • Cho, Yong-Jin (Department of Chemistry, Pukyong National University) ;
  • Kim, Dong-Soo (Department of Food Science and Technology, Kyungsung University) ;
  • Kim, Ae-Ra (College of Pharmacy, Pusan National University) ;
  • Chung, Hae-Young (College of Pharmacy, Pusan National University) ;
  • Jung, Jee-H. (College of Pharmacy, Pusan National University) ;
  • Im, Kwang-Sik (College of Pharmacy, Pusan National University) ;
  • Choi, Won-Chul (Division of Biological Sciences, Pusan National University) ;
  • Choi, Hong-Dae (Department of Chemistry, Dongeui University) ;
  • Son, Byeng-Wha (Department of Chemistry, Pukyong National University)
  • Published : 2000.09.01
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Abstract

Allenic and epoxy carotenoid, fucoxanthin (1) was isolated from the marine bacillariophycean microalga Hantzschia marina and the structure was assigned on the basis of comprehensive spectroscopic analyses. Fucoxanthin was detected only from diatom among three families (green algae, diatom and blue-green algae) of the marine microalgae tested. Fucoxanthin showed free radical scavenging activity against 1,1-diphenyl-2-picrylhydrazyl (DPPH) and peroxynitrite $(ONOO^-)$ with $IC_{50}$ values of $32\;{\mu}M\;and\;60\;{\mu}M$, respectively.

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