Tuberculosis and Respiratory Diseases
- Volume 47 Issue 2
- /
- Pages.161-171
- /
- 1999
- /
- 1738-3536(pISSN)
- /
- 2005-6184(eISSN)
Effect of Interleukin-12 on the Expression of E-selectin in Mouse Model of Lewis Lung Carcinoma
Lewis 폐암 마우스 모델에서 Interleukin-12가 E-selectin 발현에 미치는 영향
-
Lee, Sang-Haak
(Department of Internal Medicine, The Catholic University of Korea, College of Medicine) ;
- Shin, Yoon (Department of Internal Medicine, The Catholic University of Korea, College of Medicine) ;
-
Yoon, Hyoung-Kyu
(Department of Internal Medicine, The Catholic University of Korea, College of Medicine) ;
- Lee, Sook-Young (Department of Internal Medicine, The Catholic University of Korea, College of Medicine) ;
- Kim, Seok-Chan (Department of Internal Medicine, The Catholic University of Korea, College of Medicine) ;
- Kwon, Soon-Seog (Department of Internal Medicine, The Catholic University of Korea, College of Medicine) ;
-
Kim, Young-Kyoon
(Department of Internal Medicine, The Catholic University of Korea, College of Medicine) ;
- Kim, Kwan-Hyoung (Department of Internal Medicine, The Catholic University of Korea, College of Medicine) ;
- Moon, Hwa-Sik (Department of Internal Medicine, The Catholic University of Korea, College of Medicine) ;
- Song, Jeong-Sup (Department of Internal Medicine, The Catholic University of Korea, College of Medicine) ;
- Park, Sung-Hak (Department of Internal Medicine, The Catholic University of Korea, College of Medicine)
-
이상학
(가톨릭대학교 의과대학 내과학교실) ;
- 신윤 (가톨릭대학교 의과대학 내과학교실) ;
-
윤형규
(가톨릭대학교 의과대학 내과학교실) ;
- 이숙영 (가톨릭대학교 의과대학 내과학교실) ;
- 김석찬 (가톨릭대학교 의과대학 내과학교실) ;
- 권순석 (가톨릭대학교 의과대학 내과학교실) ;
-
김영균
(가톨릭대학교 의과대학 내과학교실) ;
- 김관형 (가톨릭대학교 의과대학 내과학교실) ;
- 문화식 (가톨릭대학교 의과대학 내과학교실) ;
- 송정섭 (가톨릭대학교 의과대학 내과학교실) ;
- 박성학 (가톨릭대학교 의과대학 내과학교실)
- Published : 1999.08.30
Abstract
Background: Interleukin-12 (IL-12) can induce antitumor effects in vivo. This antitumor effect is associated with T cell infiltration but the effect of IL-12 on the steps of T cell migration into the tumor tissue has not been fully elucidated. This study focused on the effect of IL-12 on the tumor growth and the metastasis and on the expression of E-selectin, an adhesion molecule which is activated endothelial specific in its expression. In addition, we studied whether the expression of E-selectin is associated with the TNF-
연구배경: Interleukin-12 (IL-12) 는 자연살해세포와 T 림프구 활성을 증가시킬 뿐 아니라 증식을 촉진시키고 mterferon-