A Case of Primary Mediastinal Embryonal Carcinoma Arising in the Posterior Mediastinum

후종격동에 발생한 원발성 종격동 태생암 1예

Primary germ cell tumors of the mediastinum are rare, accounting 1-5 % among all germ cell tumors and 10% of all neoplasms in this area. Approximately 85 % of these tumors occur in men with a mean age 29 years. 'These tumors are mainly found in the anterior mediastinum and appear grossly as large lobulated masses. They are frequently invasive at the time of diagnosis and almost 90% of patients are symptomatic. Primary nonseminomatous germ cell tumor arising in the posterior mediastinum is very rare. We report a case of 37-year old male arising from the posterior mediastinum. Serum tumors markers including alpha-fetoprotein and $\beta$-hCG which are usually elevated in germ cell tumor were not elevated. He was found to have a primary mediastinal embryonal carcinoma with pulmonary metastasis at open exploration. He was treated with debulking surgery and cisplatin-based chemotherapy, died of sepsis after 15 months postoperatively.

저자 등은 아무런 증상이 없던 37세 남자에서 후종격동에서 발생하였고 진단당시 증상이 없었으며 암표식자의 증가를 동반하지 않았던 비전형적인 원발성 종격동 태생암 l례를 경험하였기에 문헌고찰과 함께 보고하는 바이다.