Through observing effect of BOPEASAN(BPS) on an agmg white rat's Metabolic Enzyme System

노화과정(老化過程)의 흰쥐에서 보폐산(補肺散)이 폐(肺)의 대사효소계(代謝酵素系)에 미치는 영향(影響)

  • Kim, In-su (Dept. of Oriental Medicine Graduate School Tae jon University) ;
  • Go, Gwang-Chan (Dept. of Oriental Medicine Graduate School Tae jon University) ;
  • Oh, Min-suk (Dept. of Oriental Medicine Graduate School Tae jon University) ;
  • Song, Tae-won (Dept. of Oriental Medicine Graduate School Tae jon University)
  • 김인수 (대전대학교 한의과대학 재활의학교실) ;
  • 고광찬 (대전대학교 한의과대학 재활의학교실) ;
  • 오민석 (대전대학교 한의과대학 재활의학교실) ;
  • 송태원 (대전대학교 한의과대학 재활의학교실)
  • Published : 1999.09.01

Abstract

Through observing effect of BOPEASAN(BPT) on an aging white rat's metabolic enzyme system, the following conclusions were addressed 1. The quantity of the lipid peroxide in lung of was decreased meaningfully in all of experimental subject groups, relatively to counterpart groups. 2. Cytochrome P-450, Cytochrome b5, NADPH-Cytochrome P45, was decreased meaningfully in the experimental subject groups B,C and D. 3. superoxide dismutase, catarase, grutathione peroxidase, was increased meaningfully in the experimental subject groups B.C and D. 4. glutathione, glutathione S-transferase, glutathione redutase, ${\gamma}$-Glutamylcytein synthetase, had no meaningful change in the experimental subject groups. Regarding the above conclusions, the Bopeasan was affecting positively on both lipid peroxide a nd the enzyme system, as well as it has efficacy of suppressing the phenomena of aging, Therefore, the Bopeasan is, hereafter, expected to be applied clinically.

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