The Stability and Mutagenecity of $\beta$-Sitosterol Glycoside, Antimicrobial Compound from Schima wallichii sp. liukiuensis

Schima wallichii sp. liukiuensis로부터 분리된 $\beta$-Sitosterol Glycoside 항균물질의 안정성 및 돌연변이원성

Stability of the $\beta$-sitosterol glycoside from Schima wallichii sp. at various physical conditions were investigated, mutagenecity of the steroid saponin was determined by Ames test. When exposed in pH 3 to pH 8, the $\beta$-sitosterol glycoside was stable on antimicrobial activity against yeasts. The antimicrobial activity of the $\beta$-sitosterol glycoside also stable in high temperature, $N_2$, $O_2$ gas and light exposure, and metal ion. Ames test result revealed that $\beta$-sitosterol glycoside did not have any mutagenic activity. These results suggest that the $\beta$-sitosterol glycoside might be a promising candidate as a natural antimicrobial compound.