YAKHAK HOEJI (약학회지)

The Pharmaceutical Society of Korea (대한약학회)
권호 표지

Design and Synthesis of Carbo Analog of Oxetanocin Bisphosphate Derivative as $P2Y_1$ Receptor Antagonist

$P2Y_1$ 수용체 길항제로서의 옥세타노신 카보 유도체의 설계 및 합성

  • 김혜옥 (경인여자대학 산업환경공학부)
  • Published : 1999.06.01
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Abstract

In order to develop selective and competitive and competitive antagonist at the $P2Y_1$ receptor a carbocyclic oxetanocin bisphosphate derivative (7) was synthesized as a bioisostere of the lead, MRS 2179. The synthesis was started from ketene diethylacetal (1) and completed in 6 steps.

Keywords

References

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