• Title/Summary/Keyword: Carbo analog of oxetanocin bisphosphate

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Design and Synthesis of Carbo Analog of Oxetanocin Bisphosphate Derivative as $P2Y_1$ Receptor Antagonist ($P2Y_1$ 수용체 길항제로서의 옥세타노신 카보 유도체의 설계 및 합성)

  • 김혜옥
    • YAKHAK HOEJI
    • /
    • v.43 no.3
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    • pp.328-333
    • /
    • 1999

  • In order to develop selective and competitive and competitive antagonist at the $P2Y_1$ receptor a carbocyclic oxetanocin bisphosphate derivative (7) was synthesized as a bioisostere of the lead, MRS 2179. The synthesis was started from ketene diethylacetal (1) and completed in 6 steps.

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