Journal of Oriental Neuropsychiatry (동의신경정신과학회지)

The Korean Society of Oriental Neuropsychiatry (대한한방신경정신과학회)
권호 표지

Effects of Jogihaeatag(調氣解瘀湯) on the Cerebral Cortex Neuron injured by XO/XA

조기해어탕(調氣解瘀湯)이 XO／XA에 의해 손상(損傷)된 대뇌피질(大腦皮質) 신경세포(神經細胞)에 미치는 영향(影響)

  • Lee Yong-Keun (Dept. of Oriental Neurosychiatry, College of Oriental Medicine, Won Kwang University) ;
  • Kang Hyung-Won (Dept. of Oriental Neurosychiatry, College of Oriental Medicine, Won Kwang University) ;
  • Lyu, Yeoung-Su (Dept. of Oriental Neurosychiatry, College of Oriental Medicine, Won Kwang University)
  • 이용근 (원광대학교 한의과대학 신경정신과학교실) ;
  • 강형원 (원광대학교 한의과대학 신경정신과학교실) ;
  • 류영수 (원광대학교 한의과대학 신경정신과학교실)
  • Published : 1999.12.30
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Abstract

As the average life span has been lengthened and the rate of senile population has been raised, chronic degenerative diseases incident to aging have been increased rapidly and become a social problem. With this social background, recently, oxygen radicals(OR) have toxic effects on Central Nervous System and Peripheral Nervous System and cause neuropathy such as Parkinson's Disease, Alzheimer Disease. The purpose of this study is to examine the toxic effects caused by Xanthine Oxidase(XO) and the effects of herbal extracts such as Jokihaeatang(JHT) on the treatment of the toxic effects. For this purpose, experiments with the cultured cell from the cerebrums of new born mice were done. The results of these experiments were as follows. 1. X0, an oxygen radical, decreased the survival rate of the cultured cells on NR assay, MTT assay and amount of neurofilaments and increased the amount of lipid peroxidation. 2. JHT have efficacy of increasing the amount of neurofilaments.

Keywords

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