Korean Journal of Pharmacognosy (생약학회지)
- Volume 30 Issue 3
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- Pages.250-254
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- 1999
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- 0253-3073(pISSN)
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- 2288-9299(eISSN)
Effects of Yukmijihwang-tang on the Blood Pressure in Cadmium-poisoned Rats
육미지황탕이 카드뮴 중독된 흰쥐의 혈압에 미치는 영향
- Suh, Eun-Sil (College of Pharmacy, Woosuk University) ;
- Kim, Hoon (College of Pharmacy, Woosuk University) ;
- Song, Yung-Chul (College of Pharmacy, Woosuk University) ;
- Lim, Jong-Pil (College of Pharmacy, Woosuk University)
- Published : 1999.09.30
Abstract
Cadmium chloride and Yukmijihwang-tang extract (YJT), a herbal restorative were treated 3 mg/kg s.c. and 500 mg/kg p.o. respectively, and concurrently to rats, and examined the variations of the body weight, feed efficiency ratio, accumulation of cadmium in kidney, the triglyceride and cholesterol in serum, the blood pressure and heart rate of rats. The values of body weight gained and feed efficiency ratio decreased, and the other values increased significantly in cadmium-treated group, but concurrent administration with YJT showed significant recovery from the toxicity of cadmium.