A Case on Risperidone-Induced Tardive Dyskinesia

Risperidone 유발 지연성 운동장애 1례(一例)

  • Kim, Hun-Soo (Department of Psychiatry, University of Ulsan College of Medicine, Asan Medical Center) ;
  • Kim, Hyun-Sil (Department of Nursing, Kyungsan University) ;
  • Min, Byung-Kun (Department of Psychiatry, Keyo Hospital)
  • 김헌수 (울산대학교 의과대학 서울중앙병원 정신과학교실) ;
  • 김현실 (경산대학교 간호학교실) ;
  • 민병근 (계요병원 정신과)
  • Published : 1998.06.25

Abstract

Objective : Base on clinical practice, the authors report a case of tardive dyskinesia arising during the course of treatment with resperidal. Methods : This article was review and analysis of a case on risperidone-induced tardive dyskinea. Results : Mrs K, a 51-year-old woman with a 1-year history of schizophrenic disorder, gradually developed tardive dyskinetic movement of the mouth, lip, and tongue over a 4 month period(From July, 1996 to June, 1997) while taking risperidone. Initially she was treated with haloperidol and alprazolam. However, the haloperidol was subsequently discontinued because of EPS developed. From 11th March, 1997, she was observed to have a severe form of tardive dyskinesia involving her tongue, lip, and mouth. After risperidone was withdrawn at 9th May 1997, her tardive dyskinetic movement was disappeared. Conclusions : This is, to our knowledge, the first report of the onset of tardive dyskinesia in a patient taking risperidone. However, additional controlled studies of specific questions are needed ; e.g., the dose-response curves for produce tardive dyskinesia and the mechanism of producing risperidone-induced tardive dyskinea and so on.

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