YAKHAK HOEJI (약학회지)

The Pharmaceutical Society of Korea (대한약학회)
권호 표지

Antioxidative Effects of the Rhizome of Rhodiola Sachalinensis

참돌꽃 근경의 항산화작용

  • Published : 1998.06.01
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Abstract

Ihe purpose of this study was to determine the antioxidative effects of Rhodiola sachalinensis. Rhodiola methanol extract was fractionated sequentially with dichlorometha ne and butanol. Each Rhodiola fraction (water, MeOH, BuOH and $CH_2Cl_2$ fractions) showed the potent superoxide dismutase (SOD) activity, and had inhibitory effects on peroxide value of linoleic acid ($40{\sim}57%$) and lipid peroxidation ($47{\sim}70%$). In $Fe^{2+}$/ascorbate system-induced rat liver microsome. Rhodiola methanol extract also recovered carbon tetrachloride-induced decrease in SOD by 42% and catalase activities by 50%, and had inhibitory effects (54%) on carbon tetrachloride-induced lipid peroxidation in rat liver microsome. These results suggest that Rhodiola sachalinensis has the antioxidative effects.

Keywords

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