A Study on the Mathematical Modeling of Human Pharyngeal Tissue Viscoelasticity

인두조직의 점 탄성특성의 수학적모델링에 관한 연구

  • 김성민 (연세대학교 의과대학 의용공학교실) ;
  • 김남현 (연세대학교 의과대학 의용공학교실)
  • Published : 1998.10.01

Abstract

A mathematical model of viscoelasticity on the material property of human pharyngeal tissue utilizing Y.C. Fung's Quasi-linear viscoelastic theory is proposed based on cyclic load, stress relaxation, incremental load, and uniaxial tensile load tests. The material properties are characterized and compared with other biological materials' results. The mathematical model is proposed by combining two characteristic functions determined from the stress relaxation and uniaxial tensile load tests. The reduced stress relaxation function G(t) and elastic response function S(t) are obtained from stress relaxation test and uniaxial tensile load test results respectively. Then the model describing stress-time history of the tissue is implemented utilizing two functions. The proposed model is evaluated and validated by comparing the model's cyclic behaviour with experimental results. The model data could be utilized as an important information for constructing 3-dimensional biomechanical model of human pharynx using FEM(Finite Element Method).

Y.C. Fung[1]에 의한 연조직의 점탄성에 관한 수학적 모델이론 (Fung's Quasi-linear vlscoelastic theory)을 이용하여 인간의 인두조직의 점탄성(vlscoelatlcity)특성을 측정하기 위하여 반복성하중(cyclic load) ,응력완화 (tensile stress relaxation), incremental load, 그리고 일축성인장 (uniaxial tensile) 시험 등을 실시하였다. 실험적으로 측정한 인두조직의 점탄성특성이 이미 조사된 다른 조직의 점탄성특성과 정량적으로 비교되었다. 인두조직의 점탄성특성의 정량화를 위하여 Y.C.Fung의 수학적 모델이 적용되었는데 응력완화(tensile stress relaxation) 시험 측정결과로부터 도출된 표준화된 응력완화(reduced stress relaxation)함수 G(t)와 일축성인장(uniaxial tensile)시험에서 도출된 탄성반응(elastic response)함수 5(t)를 이용하여 시간에 따른 응력의 궤적을 산출하여 이를 반복성 하중(cyclic load)실험에서 측정된 결과와 비교, 분석하였다. 이러한 인두조직의 점탄성특성에 관한 연구결과는 향후 유한요소를 이용한 인두의 생체역학적 모델의 기본 데이터로 이용될 수 있다.

Keywords

References

  1. Stress-strain history relations of soft tissues in simple elongation. Biomechanics: Its foundations and objectives, eds. Fung, Y.C.B.
  2. Head Neck Surg v.9 Examination after total laryngectomy using manoflourography McConne FMS;Mendelsohn MS;Logemann JA
  3. Dysphagia v.6 Interpretation of intraluminal manometic measurements in terms of swallowing mechanics Brasseur JG;Dodds WJ
  4. AJR v.153 Interactive computer program of biomechanical analysis of videoflourographic studies of swallowing Logemann JA.;Kahrilas, PJ;Begelman J;Pauloski, BR
  5. Otolaryngology Head and Neck Surg. v.100 no.1 Qyantitative assessment of pharyngeal bolus driving forces Danko Cerenko;Fred MS;McConnel;Richard Jackson
  6. Physiolocal Reviews v.37 Deglutition: Pharyngeal stage Bosma, JF
  7. Journal of Biomechanical Engineering v.102 Visco-elasticity of passive cardiac muscle Pinto JG;patiticci PJ
  8. ASME BED v.22 A single integral finite strain (SIFS) viscoelastic model of ligaments and tendons Johnson GA;Rajagopal KR;Woo SLY
  9. Journal of Biomechanics v.9 Measurements of nonhomogeneous, directional mechanical properties of articular cartilage in tension Woo SLY;Akeson WH;Jemmott GF
  10. J. Acoust. Soc. Am. v.78 no.6 Viscoelastic modeling of canine vocalis muscle in relaxation Alipour-Haghighi F;Titz IR
  11. Arch Phys Med Rehabil v.76 Malnutrition in stroke patients on the rehabilitation service and at follow-up: prevalence and predictors Fineston HM;Greene-Finestone LS;Wilson ES;Teasell RW
  12. Br Med J v.295 Dysphagia in acute stroke Gordon C.;Hewer RL;Wade DT
  13. otolaryngol Head Neck Surg v.94 Asporation and nasogastric intubation Alessi DM;Berci G.
  14. Arch Otolaryngol Head Neck Surg v.116 Manometry and electromyography of the pharyngeal muscles in patients with dyaphagia Elidan J;Shochina M;gonen B;Gay I
  15. Arch Phys Med Rehabil v.76 Malnutrition in stroke patients on the rehabilitation service and at follow-up:prevalence and predictors Fineston HM;Greene-Fonestone LS;Wilson ES;Teasell RW
  16. Br Med J v.295 Dysphagia in acute stroke Gordon C;Hewer RL;Wade DT
  17. Dysphagia v.8 Art and science of history taking in the patient with difficulty swallowing Hendrix TR
  18. Intensive Care Med v.14 A retrospective survey of treatment and mortality in asporation pneumonia Hicking K;Howard R
  19. Arch Phys Med Rehabil v.73 Dysphagia following stroke: Quantitative evaluation of pharyngeal transti times Johnson ER;McKenzie SW;Rosenquist CJ;Lieberman JS;Sievers AE
  20. Dysphagia v.9 Indications and techniques of endoscopy of cervical dysphagia: comparison with radiographic techniques Kidder TM;Langmore SE;Martin BJ
  21. Dysphagia v.8 The value of endoscopy and endosongraphy in the diagnosis of the dyaphagic patients Lorenz R;Jorysz G.;Classen M
  22. Arch Phys Med Rehabil v.73 Early intervention in severe head injury: long-term benefits of a formalized program Mackay LE;Bernstein BA;Champman PE;Morgan AS;Milazzo LS
  23. Head Neck v.16 Scintigraphic assesment of aspiration in head and neck cancer patients with trachestomy Muz J;Hamlet S;Mathog R;Farris R
  24. Dysphagia v.8 A protocol for the videoflyourographic swallowing study Palmer JB;Kuhlemeier KV;Tippett MA;Lynch C
  25. Arch Phys Med Rehabil v.69 Aspitation in rehabilitation patients: video fluoroscopy vs bedside clinical assessment Splaingard ML;Hutchins B;Sulton LD;Chaudhuri G
  26. Arch Phys Med Rehabil v.75 Laryngeal movement oropharyngeal pressure, and submental muscle conraction during swallowing Schultz JL;Perlman Al;VanDale DJ
  27. J. biomech. Engng. v.112 The anatomy and function of the anterior cruciate ligament as determined by clinical and morphological studies Kennedy, J. C.;Weinberg, H. W.;Wilson, A. S.
  28. Inproc. Biomech. Symp. ASME v.ADM-2 Stress-strain history relations of rabbit mesentery in simple elongation Chen, Y. L.;Fung, Y. C.