The Fibrinolytic Activity of Kimchi and its Ingredients in vivo and in vitro

In vivo와 in vitro에서 김치 및 김치재료의 피브린 분해활성

  • 송영옥 (부산대학교 식품영양학과 및 김치연구소) ;
  • 김미정 (부산대학교 식품영양학과 및 김치연구소) ;
  • 송영선 (인제대학교 식품영양학과)
  • Published : 1998.08.01

Abstract

Fibrionolytic activity(FA) of kimchi in rat and FAs of water and methanol extracts of kimchi ingredient were determined using fibrin plate method to see where the active principles for FA are present in kimchi. Nine Sprague-Dawley per each group were fed diet containing 3, 5 or 10% of freeze dried kimchi for 6 weeks. The FA of plasma obtained from 10% kimchi group showed stronger FA than that of control. FAs of 3 and 5% kimchi group were not noticeable. FA from methanol extract of kimchi was approximately 6 times higher than that from water extract assuming that the active material may be present in a fat soluble fraction. From water extract of kimchi ingredients, dropwort, green onion, radish and baechu showed FA in descending order. And from methanol extracts, red pepper powder, radish, green onion and baechu showed FA in decending order. The Fa of methanol extract of red pepper powder was the most noticeable among samples.

Keywords

References

  1. 3차년도 농림수산 특정연구과제 진도보고서 항암 및 항노화 기능성 김치무리의 개발에 관한 연구 송영옥
  2. 한국식품영양과학회지 v.26 no.507 흰쥐에서 김치식이가 조직과 분변의 지질조성과 Apo단백 및 Thyroxine 농도에 미치는 영향 권명자;송영옥;송영선
  3. 부산대학교 대학원 박사학위 논문 배추김치의 동맥경화 예방효과에 관한 연구 권명자
  4. 한국식품영양과학회지 v.26 no.1208 In vivo와 in vito에서 김치가 혈액성상과 면역세포배양에 미치는 영향 김미정;권명자;송영옥;이은경;윤현주;송영선
  5. 한국영양식량학회지 v.1 no.169 김치의 영양학적 평가와 항돌연변이 및 항암효과 박건영
  6. J. Food. Sci. Nutr. v.2 no.241 Inhibitory effects of kimchi extracts on carcinogen-induced cytotoxicity and transformation in $C_3$H/10T1/2 cells 최명원;김광혁;김소희;박건영
  7. 한국식품영양과학회지 v.26 no.563 갓김치의 발효과정 중 chlorophylls 및 carotenoids의 변화와 동획분의 항산화성 송은승;전영수;최홍식
  8. 한국영양식량학회지 v.25 no.261 발효시간이 다른 김치의 우육 지방질에 대한 항산화성 이영옥;박건영;최홍식
  9. 한국식품영양과학회지 v.26 no.814 김치추출물의 활성산소에 대한 피부세포 독성 완화효과 류승희;전영수;권명자;문정원;이영순;문갑순
  10. 한국식품영양과학회지 v.26 no.998 김치주·부재료의 활성산소에 대한 피부세포 독성 완화효과 류승희;전영수;문정원;이영순;문갑순
  11. In hemostasis and thrombosis Walsh, P.N.
  12. Experi v.28 no.254 Antihypercholesterolemic effect of sulfur contining amino acid,S-methyl-L-cysteine sulfoxide isolated from cabbage Fujiwara,M.
  13. Preventive Medicine v.16 no.670 Garlic(Allium sativum) and Onion (Allium cepa):A review of their relationship to cardiovascular disease Kendler, B. S.
  14. Arzneim.-Forsch. Durg Res v.41(II) no.8 Inhibition of cholesterol biosynthesis by a water-soluble garlic extract in primary cultures of rat hepatocytes Gebhardt,R.
  15. 한국식품영양과학회지 v.26 no.1194 매운맛 선호도가 사람의 말초혈액에서 분리한 면역세포 활성에 미치는 영향 표종옥;한인섭;김병삼;유리나
  16. Agric. Biol. Chem. v.51 no.75 Enhancement by capsaicin of catecholamine from adrenal medulla Watanabe, T.;Kawada T.;Iwai, K.
  17. Pharmacological Reviews v.38 no.773 The neuropharmacology of capsaicin:Review of some recent observation Buck, S. H.;Burks, T. F.
  18. Carcinogenesis v.16 no.2467 Chemoprotective effects of capsaicin and diallyl sulfide against mutagenesis or tumorigenesis by vinyl carbamate and N-nitrosodimethylamine Surh, Y.J.;Lee, R.C.;Park, K.K.;Mayne, S.T.;Liem, A.;Miller, J.A.
  19. 한국식품영양과학회 제41차 춘계학술대회초록 식이 capsaicin이 in vivo에서 자발성 고혈압 흰쥐의 혈압상태 및 혈중 지질수준에 미치는 영향 유리나;최윤정;박수아;정대균;남희섭;신재익
  20. 중앙대학교 석사학위논문 Capsaicin이 SHR에서 혈압에 미치는 영향 김옥순
  21. Einfluss regelmaessiger Aufnahme von Sauerkraut und Kimchi auf verschie den Blutparameter Ernaehrungsphysiologische Wirkungen laktofermentierter Kohlgemuese Hwang I.J.
  22. 생명과학회지 v.5 no.203 김치의 혈전용해작용 정영기;양웅석;강정옥;공인수;김정옥
  23. Biochemical Pharmacology v.29 no.3169 Inhibition of fatty acid oxygenases by onion and garlic oils Vanderhoek, J. Y.;Makhja, A. N.;Bailey, J. M.
  24. Atherosclerosis v.28 no.155 Effect of essential oil of garlic on serum fibrinolytic activity in patients with coronary artery disease Bordia, A. K.;Joshi, H.;Sanadhya, Y. K.;Bhu, N
  25. Ind. J. Med. Res v.69 no.776 Effect of dietary garlic and onion on serum lipid profile in Jain community Sainani, G. S.;Desai, D. B.;Gorhe, N. H.;Natu, S. M.;Pise, D. V.;Sainani, P. G.
  26. Methods in carbohydrate chemistry Whistler,R.L.;Wolform,M.L.
  27. J. Assoc. Off. Anal. Chem. v.77 no.1017 Determination of insoluble,soluble and total dietary fiber in foods and food products:Inter-laboratory study Prosky,L.;Asp,N.;Schweizer,T.F.;Devries,J.W.;Furda,J.
  28. Ind. J. Med. Res. v.54 no.48 Effect of onion on serum cholesterol, Blood-coagulation factrors and fibrinolytic activity in alimentary lipemia Gupta,N.N.;Mehrotra,R.M.L.;Sircar,A.R.
  29. J. Assoc. Phys. Ind. v.19 no.301 Study of effects of onion feeding on fibrinolytic activity of blood Jain, R.C.
  30. Atherosclerosis v.38 no.417 The effect of fried vs.raw garlic on fibrinolytic activity in man Chutani, S. K.;Bordia, A.
  31. Atherosclerosis v.21 no.15 Effect of the essential oils of garlic and onion on alimentary hyperlipemia Bordia, A.K.;Bansal,H.C.;Arora,S.K.;Singh,S.V.
  32. Atherosclerosis v.39 no.447 Comparative effects of clofibrate, garlic, and onion on alimentary hyperlipemia Arora, R.C.;Arora, S.
  33. 김치의 과학(한국식품과학회 심포지움발표논문집 김치의 영양생리학적 평가 오영주;황인주;Leitzmann,C.
  34. Am. J. Clin. Nutr. v.30 no.1380 Effect of garlic on serum lipids,coagulability and fibrinolyitc activity of blood Jain, R. C.
  35. Preventive Mdeicine v.16 no.676 Garlic(Allium sativum) and Onion (Allim cepa):Their relationship to cardiovascular disease Kendler, B. S.
  36. South. African. J. Sci v.91 no.68 Galic(Allium sativum)for disease prevention Srivastava, K. C.;Bordia, A.;Verma, S. K.
  37. Brain Res v.123 no.323 The effect of capsaicin on the adenylate cylase activity of rat brain Jancso, G.;Wollemann, M.