Parasites, Hosts and Diseases
- Volume 36 Issue 1
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- Pages.33-36
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- 1998
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- 2982-5164(pISSN)
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- 1738-0006(eISSN)
Effect of Cryptosporidium baileyi infection on antibody response to sRBC in chickens
닭에 있어서 닭와포자충 감염이 sRBC에 대한 항체반응에 미치는 영향
- Lee, Jae-Gu (Bio-safety Research Institute, Chonbuk National Univerisity) ;
- Kim, Hyeon-Cheol (Bio-safety Research Institute, Chonbuk National Univerisity) ;
- Park, Bae-Geun (Bio-safety Research Institute, Chonbuk National Univerisity)
- Published : 1998.03.01
Abstract
Hemagglutinin (HA) titers to SRBC were chronologically observed in chickens orally inoculated at 2 days of age with 5 × 105 oocysts of Cwptosporidium bniLeWi. All the infected chickens exhibited negligible HA titers by 44 days postinoculation (Pl) . The titers were elevated as time progressed. and peaked on day 52 Pl, declined gradually thereafter, and eventually reached to normal titers on day 92 Pl. On the contrary, the titers in uninfected chickens were higher in comparison with infected chickens during the experiment. Chickens infected with the protozoa showed normal oocyst shedding profiles during this period. These data suggest that C. bnilewi infection suppress development of humoral immunity to SRBC in chickens. It is possible that impairment of the bursa of Fabricius by cryptosporidiosis rendered chickens vulnerable to other pathogens.
닭에 있어서 닭와포자충 감염이 면역억제에 미치는 영항을 규명하기 위한 일환으로 150마리의 2 일령 SPF 병아리에