Applied Biological Chemistry
- Volume 41 Issue 4
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- Pages.261-264
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- 1998
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- 2468-0834(pISSN)
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- 2468-0842(eISSN)
Synthesis and Configuration Determination of Styrylquinolines as Leukotriene $D_4$ Antagonist Precursors
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Koh, Dong-Soo
(Department of Applied Chemistry, Dongduk Women's University)
;
- Koo, Bon-Jeong (Department of Applied Biology and Chemistry, Kon-Kuk University) ;
- Yong, Yeon-Joong (Department of Applied Biology and Chemistry, Kon-Kuk University) ;
- Lim, Yoong-Ho (Department of Applied Biology and Chemistry, Kon-Kuk University)
- Published : 1998.06.30
Abstract
Differently substituted styrylquinoline derivatives (6-9) were synthesized by condensation of quinaldine (1) and corresponding substituted benzaldehydes (2-5). Their relative configuration at C11-C12 and coupling patterns were determined by NMR techniques.