Journal of Pharmaceutical Investigation
- Volume 28 Issue 1
- /
- Pages.15-23
- /
- 1998
- /
- 2093-5552(pISSN)
- /
- 2093-6214(eISSN)
Preparation and Skin Permeation of Poloxamer 407 Hydrogel with Extract of Centella $asiatica-{\beta}-Cyclodextrin$ Solid Dispersion System
병풀(Centella asiatica) 엑스-베타시클로덱스트린 고체 분산체를 함유한 폴록사머 407 히드로겔 제조 및 피부투과
- Kim, Kyoung-Kook (College of Pharmacy, Chungnam National University) ;
- Kwak, Eun-Sun (College of Pharmacy, Chungnam National University) ;
- Lee, Gye-Won (College of Pharmacy, Chungnam National University) ;
- Park, Jin-Kyu (Dong kook Pharm. Co., Ltd.) ;
- Park, Mork-Soon (Dong kook Pharm. Co., Ltd.) ;
- Jee, Ung-Kil (College of Pharmacy, Chungnam National University)
- 김경국 (충남대학교 약학대학) ;
- 곽은선 (충남대학교 약학대학) ;
- 이계원 (충남대학교 약학대학) ;
- 박진규 (동국제약 주식회사) ;
- 박목순 (동국제약 주식회사) ;
- 지웅길 (충남대학교 약학대학)
- Published : 1998.03.20
Abstract
Extract of Centella asiatica(ECA), which is poorly water-soluble extract from the Centella asiatica is known to express excellent wound healing properties.
Keywords
- ECA;
- Asiaticoside;
- Genin(madecasic acid:asiatic acid=1:1);
- Poloxamer;
- Gel;
- Viscosity;
- ${\beta}-CD$;
- Skin permeation;
- Solid dispersion system