Natural Product Sciences
- Volume 4 Issue 4
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- Pages.230-233
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- 1998
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- 1226-3907(pISSN)
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- 2288-9027(eISSN)
Evaluation of Anti-inflammatory Activity of Asparagus racemosus Willd. (Liliaceae) root extract
- Mandal, Subhash C. (Division of Pharmacognosy, Dept. of Pharmaceutical Technology, Faculty of Engineering and Technology, Jadavpur University) ;
- Maiti, B.C. (Indian Institute of Chemical Biology) ;
- Maity, Tapan K. (Division of Pharmacognosy, Dept. of Pharmaceutical Technology, Faculty of Engineering and Technology, Jadavpur University) ;
- Pal, M. (Division of Pharmacognosy, Dept. of Pharmaceutical Technology, Faculty of Engineering and Technology, Jadavpur University) ;
- Saha, B.P. (Division of Pharmacognosy, Dept. of Pharmaceutical Technology, Faculty of Engineering and Technology, Jadavpur University)
- Published : 1998.12.01
Abstract
The methanol extract of Asparagus racemosus root was evaluated for its anti-inflammatory activity on carrageenin and serotonin-induced rat hind paw oedema models. The extract (200 and 400 mg/kg) showed maximum inhibition of oedema of 18.6% and 33.7% at 3 h with carrageenin and 22.2% and 40.5% at 5 h with serotonin-induced rat paw oedema respectively. The experimental models tested, where the effect produced by the extract was compared to that of phenylbutazone, a prototype non-steroidal anti-inflammatory drug.
Keywords
- Asparagus racemosus root extract;
- anti-inflammatory activity;
- carrageenin and serotonin-induced;
- phenylbutazone