Natural Product Sciences
- Volume 4 Issue 4
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- Pages.226-229
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- 1998
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- 1226-3907(pISSN)
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- 2288-9027(eISSN)
Antihepatotoxic Activity of Cassia tora Leaf Extract
- Maity, Tapan K. (College of Pharmaceutical Sciences) ;
- Mandal, Subhash C. (Department of Pharmaceutical Technology, Faculty of Engineering and Technology, Jadavpur University) ;
- Pal, M. (Department of Pharmaceutical Technology, Faculty of Engineering and Technology, Jadavpur University) ;
- Saha, B.P. (Department of Pharmaceutical Technology, Faculty of Engineering and Technology, Jadavpur University)
- Published : 1998.12.01
Abstract
Methanolic extract of Cassia tora leaves was evaluated for its hepatoprotective activity in rats by inducing hepatotoxicity with paracetamol (acute model). The extract at a dose of 400 mg/kg orally exhibited significant protective effect by lowering the serum levels of transaminase (SGOT and SGPT), bilirubin, and alkaline phosphatase (ALP). The effects produced were comparable to that of a standard hepatoprotective agent.