Antioxidant Activities of Extracts from Fruiting Bodies of Mushrooms

버섯추출물의 항산화활성에 관한 연구

  • Published : 1998.03.30

Abstract

Antioxidant activities of 80% ethanol extracts of 63 species of mushroom fruiting bodies were investigated. The ethanol extracts from Daedalea dickinsii, Armillariella mellea, and Fomitella fraxinea showed markedly inhibition on lipid peroxidation in rat liver microsome. The extracts from Daedaleopsis tricolor, Trametes suaveolens, Armillariella mellea, Trichaptium abietinum, Daedalea dickinsii, Fomitella fraxinea, Tylophilus neofelleus, Boletellus obscurecoccineus, and Xerocomus subtomentosus significantly inhibited the hepatic aldehyde oxidase activity, and the extracts from Daedaleopsis tricolor, Armillariella mellea, Daedalea dickinsii, and Fomitella fraxinea slightly stimulated the hepatic SOD activity. These results suggest that Daedalea dickinsii, Armillariella mellea, and Fomitella fraxinea contain the bioactive substances for natural antioxidant and may be useful for development of antioxidant from mushrooms.

버섯의 항산화 활성을 검색하기 위하여 63종의 버섯자실체를 80% 에탄올로 추출한 후 각각의 버섯추출물이 지질과산화반응, AO 및 SOD의 활성도에 미치는 효과를 관찰하였다. 테미로버섯(D. dickinsii), 뽕나무버섯(A. mellea) 및 아카시재목버섯(F. fraxineu)의 추출물이 간조직 microsome의 지질과산화반응을 억제시켰으며, A. mellea, D. dickinsii, F. fraxinea, 삼색도장버섯(D. tricolor), 송편버섯(T. suaveolens), 옷솔버섯(T. abietinum), 제주쓴맛그물버섯(T. neofelleus), 노란그물버섯(B. obscurecoccineus) 및 산그물버섯(X. subtomentosus) 등의 추출물은 간 세포질 내의 초산화 이온의 생성효소인 AO 활성을 크게 억제시켰다. 한편, D. tricolor, A. mellea, D. dickinsii, 및 F. fraxinea 등의 추출물은 간 세포질의 SOD의 활성을 증가시켰다. 이상의 결과로부터 특히 A. mellea, D. dickinsii 및 F. fraxinea로부터 항산화활성 성분의 분리정제 및 생리활성물질의 개발에 대한 가능성이 제시되었다.

Keywords

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