대한한방내과학회지 (The Journal of Internal Korean Medicine)

대한한방내과학회 (The Society of Internal Korean Medicine)
권호 표지

단삼보혈탕(丹蔘補血湯)이 혈청(血淸) gastrin, secretin 및 중추신경계(中樞神經系)에 미치는 영향(影響)

Effects of Dansambohyultang on serum gastrin, secretin release and CNS

  • 여은경 (경희대학교 한의과대학 비계내과학교실) ;
  • 윤상협 (경희대학교 한의과대학 비계내과학교실) ;
  • 류봉하 (경희대학교 한의과대학 비계내과학교실) ;
  • 박동원 (경희대학교 한의과대학 비계내과학교실) ;
  • 류기원 (경희대학교 한의과대학 비계내과학교실)
  • Yeo, Eun-Kyung (Dept. of Oriental Internal Medicine, Graduate School, Kyung Hee University) ;
  • Yun, Sang-Hyup (Dept. of Oriental Internal Medicine, Graduate School, Kyung Hee University) ;
  • Rue, Bong-Ha (Dept. of Oriental Internal Medicine, Graduate School, Kyung Hee University) ;
  • Park, Dong-Won (Dept. of Oriental Internal Medicine, Graduate School, Kyung Hee University) ;
  • Rue, Gi-Won (Dept. of Oriental Internal Medicine, Graduate School, Kyung Hee University)
  • 발행 : 1998.12.01
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초록

This study was conducted to investigate effects of Dansambohyultang on serum gastrin, secretin release and CNS in rats and mice. One group of seven rats was intactly in normal condition, the other group of seven rats was respectively heated, starved, and stressfully immobilized. The third group of seven rats was provided with Dansambohyultang before the stress, and the forth one after the stress. And, gastrin concentration and secretin concentration were measured. Mice were studied with regard to convulsion time, total sleep time and analegic effects on cental nerve system. The results were as follows: 1. Gastrin concentration was significantly decreased, and secretin concentration was significantly increased. 2. Analegic effect by acetic acid method was recognizably observed. 3. Effect of total sleep time done by pentobarbital-Na was recognizably observed. 4. Anti-convulsion effects induced by strychnine, picrotoxin and caffeine were recognizable. It is inferred from above results that Dansambohyultang inhibits gastin release, stimulates secretin release and palliate the pain.

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