Korean Journal of Biological Psychiatry (생물정신의학)

The Korean Society of Biological Psychiatry (대한생물정신의학회)
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The Role of Serotonin in Pathology and Treatment of the Mood Disorders

기분장애의 병리와 치료에 있어 세로토닌의 역할

  • Jung, In Kwa (Department of Psychiatry, College of Medicine, Korea University) ;
  • Kim, Jin Se (Department of Psychiatry, College of Medicine, Korea University)
  • 정인과 (고려대학교 의과대학 정신과학교실) ;
  • 김진세 (고려대학교 의과대학 정신과학교실)
  • Published : 1997.12.25
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Abstract

The serotonin has been known to play important roles in pathology of the mood disorders. We summerize the evidences of serotonin in pathology of the mood disroders in a view of neuroanatomical and neurochemical aspects. Nowaday, the selective serotonin reuptake inhibitors(SSRIs) may be practically the first line of antidepressants with traditional tricyclic antidepressants(TCAs). Authors review the role of serotonin in the treatment of the mood disorders, in a view of the general considerations in selecting antidepressants, pharmacology, therapeutic indications, side effects, doses of medication, drug-discontinuation syndrome, drug-to-drug interactions, and special therapeutic situations.

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