The Korean Journal of Pain
- Volume 10 Issue 2
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- Pages.208-213
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- 1997
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- 2005-9159(pISSN)
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- 2093-0569(eISSN)
Treatment of Epidural-Morphine-Induced Pruritus: Propofol Versus Naloxone
경막외 Morphie 투여시 생기는 소양증에 대한 Propofol과 Naloxone의 효과 비교
- Park, Chung-Hyun (Department of Anesthesiology, Pochon CHA University College of Medicine) ;
- Jung, Hyun-Jung (Department of Anesthesiology, Pochon CHA University College of Medicine)
- Published : 1997.11.22
Abstract
Background: Pruritus is the most frequent undesirable symptom associated with epidural morphine. It is unpleasant and often difficult to treat. Naloxone is presently the drug of first choice for treating this symptom. Naloxone however decrease the pain threshold in some cases. Recently it was reported subhypnotic doses of propofol were efficient in relieving epidural-morphine-induced pruritus(EMIP). In a prospective. randomized, double-blinded clinical trial, we compared the efficacy of propofol and naloxone for treatment of EMIP. Methods: Forty patients with EMIP were allocated to receive either 20 mg propofol, or 1.5
Keywords
- Analgesics: morphine;
- Anesthetics, intravenous: propofol;
- Antagonist, narcotics: naloxone;
- Complications: pruritus