Journal of the Korean Society of Food Science and Nutrition (한국식품영양과학회지)

The Korean Society of Food Science and Nutrition (한국식품영양과학회)
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Effects of Extract of Pueraria radix on Hematological Properties and Lead Level of the Tissues of the Pb-administered Rats

갈근추출물이 납 중독된 흰쥐의 혈액성분 및 조직의 납 축적에 미치는 영향

  • 이정숙 (고신대학교 식품영양학과) ;
  • 김명주 (신일전문대학 식품영양학과) ;
  • 박은미 (영남대학교 식품영양학과)
  • Published : 1997.06.01
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Abstract

This study was designed to investigate the effects of Korean Pueraria radix extract in Pb administered rats. Pb exposed rats were given 1% Pb in the diet. $\delta$-Adminolevulinic acid(DALA) and urinary glucose levels were increased with Pb administration and were lower in the Pb group than in the group administered Pb alone. Hematocrit value was decreased with Pb administration and was higher in the Pb group than in the C-Pb grou. $\delta$-Aminolevulinic acid dehydratase (DALAD) activity was decreased in the Pb group. ALT and AST were increased by Pb added and were lower in the Pb group than in the C-Pb group. Serum Pb content was higher in the Pb exposed rats than in the control groups, and no significant difference was found due to extract of Pueraria radix supplementation. Levels of liver, kidney and femur lead were reduced by Pueraria radix. Lead contents in feces and urine were higher in the Pb added groups than in the control group, and level of feces lead was increased by extract of Pueraria radix.

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References

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