Archives of Pharmacal Research
- 제20권1호
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- Pages.72-75
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- 1997
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- 0253-6269(pISSN)
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- 1976-3786(eISSN)
Synthesis and Anti-inflammatory and Analgesic Activities of Phenoxyalkanoic Acid Derivatives
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Shin, Kuk-Hyun
(Natural Products Research Institute, Seoul National University) ;
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Lee, Eun-Bang
(Natural Products Research Institute, Seoul National University) ;
- Park, Sang-Woo (Division of Applied Sciences, Korea Institute of Science and Technology) ;
- Shin, Kye-Jung (Division of Applied Sciences, Korea Institute of Science and Technology) ;
- Kim, Dong-Chan (Division of Applied Sciences, Korea Institute of Science and Technology) ;
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Kim, Dong-Jin
(Division of Applied Sciences, Korea Institute of Science and Technology)
- 발행 : 1997.02.01
초록
The synthesis of phenoxyalkanoic acid derivatives and their anti-inflammatory and analgesic activities are described. Analysis of structure-activity relationships shows that in trichlorophenoxy derivatives anti-edematous potency is associated with the presence of 1-thiopropyl moiety and 2 or 40aminopyridyl moiety at
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