Korean Journal of Food Science and Technology (한국식품과학회지)
- Volume 29 Issue 1
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- Pages.167-172
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- 1997
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- 0367-6293(pISSN)
Effects of Combined Preparation (DWP715) Containing Alaska pollack Extract, Maltol, Ascorbic Acid and Nicotinamide on Decreasing of Blood Alcohol Concentration, Anti- fatigue and Anti-oxidation
북어엑스 및 말톨 함유 복합 조성물(DWP715)의 혈중 알콜농도 저하, 항피로 및 항산화 효과
- Cho, Jae-Youl (R & D Center, Daewoong Pharm. Co., Ltd.) ;
- Kim, Ae-Ra (R & D Center, Daewoong Pharm. Co., Ltd.) ;
- Yeon, Je-Duk (R & D Center, Daewoong Pharm. Co., Ltd.) ;
- Lim, Seung-Wook (R & D Center, Daewoong Pharm. Co., Ltd.) ;
- Lee, Jae-Hwi (R & D Center, Daewoong Pharm. Co., Ltd.) ;
- Yoo, Eun-Sook (R & D Center, Daewoong Pharm. Co., Ltd.) ;
- Yu, Young-Hyo (R & D Center, Daewoong Pharm. Co., Ltd.) ;
- Park, Myung-Hwan (R & D Center, Daewoong Pharm. Co., Ltd.)
- 조재열 ((주) 대웅제약 중앙연구소) ;
- 김애라 ((주) 대웅제약 중앙연구소) ;
- 연제덕 ((주) 대웅제약 중앙연구소) ;
- 임승욱 ((주) 대웅제약 중앙연구소) ;
- 이재휘 ((주) 대웅제약 중앙연구소) ;
- 유은숙 ((주) 대웅제약 중앙연구소) ;
- 유영효 ((주) 대웅제약 중앙연구소) ;
- 박명환 ((주) 대웅제약 중앙연구소)
- Published : 1997.02.01
Abstract
Effect of combined preparation (DWP715) containing Alaska pollack extract, maltol, ascorbic acid and nicotinamide on decreasing of blood alcohol was evaluated in human blood. Treatment of DWP715 prior to administration of 25% alcohol (100 mL) decreased alcohol concentration in blood and showed significant difference after 2 hours. The pharmacokinetic parameters such as area under the concentration-time curve (AUC),
1. 정상 성인 남자를 대상으로 한 25%의 알콜 100 ml 섭취시 DWP715는 전 대상인에서
Keywords
- Alaska pollack;
- maltol;
- ascorbic acid;
- nicotinamide;
- pharmacokinetics;
- alcohol;
- lipid peroxidation;
- anti-fatigue;
- anti-oxidation;
- LDH;
- GOT;
- GPT;
- adrenal weight;
- restraint stress model