YAKHAK HOEJI (약학회지)
- Volume 40 Issue 4
- /
- Pages.375-381
- /
- 1996
- /
- 0377-9556(pISSN)
- /
- 2383-9457(eISSN)
Effects of Crystal Modification on Dissolution and Stability of Droperidol
드로페리돌의 용출과 안정성에 미치는 결정형의 영향
-
Son, Yeong-Taek
(College of Pharmacy, Duksung Women's University)
;
- Jeong, Sin-Hui (College of Pharmacy, Duksung Women's University)
- Published : 1996.08.01
Abstract
Five crystal modification of droperidol were prepared by recrystallization. They were characterized by UV spectrophotometer, DSC, and X-ray crystallography. Their dissolution pa tterns were also investigated. After storage of 2 months at 100% humidity, all polymorphic modifications were transformed.
Keywords
- Droperidol;
- DSC;
- x-ray crystallography;
- dissolution;
- stability;
- crystal modification;
- humidity;
- recrystallization