DSC and TGA Thermal Analysis for the Interaction between Poly(2-hydroxyethylmethacrylate) and Amino Acids

Poly(2-hydroxyethylmethacrylate)와 아미노산과의 상호작용에 관한 DSC와 TGA 열분석에 관한 연구(Ⅰ)

  • Kim, Ui Rak (Department of Chemistry, Keimyung University) ;
  • Jeong, Bong Jin (Department of Chemistry, Keimyung University) ;
  • Jeong, Sung Uk (Department of Chemistry, Keimyung University) ;
  • Min, Kyung Sub (Department of Chemistry, Keimyung University) ;
  • Lee, Myung Jae (Department of Natural Science, Chemistry Section, Medical College Catholic University) ;
  • Nam, Won Mo (Department of Chemistry, Keimyung University) ;
  • Park, Hae Jung (Department of Chemistry, Keimyung University)
  • 김의락 (계명대학교 자연과학대학 화학과) ;
  • 정봉진 (계명대학교 자연과학대학 화학과) ;
  • 정성욱 (계명대학교 자연과학대학 화학과) ;
  • 민경섭 (계명대학교 자연과학대학 화학과) ;
  • 이명재 (가톨릭대학교 의과대학 자연과학교실 화학과) ;
  • 남원모 (계명대학교 자연과학대학 화학과) ;
  • 박혜정 (계명대학교 자연과학대학 화학과)
  • Published : 19960600

Abstract

The interaction between poly(HEMA) which is material of contact lens containing about 45% water and amino acids (alanine, arginine, methionine, proline, glycine, serine, lysine) have been studied by using the thermal analysis methods through DSC and TGA. The experimental results of DSC and TGA were shown that lysine, arginine and alanine have the most stable interaction between poly(HEMA) and amino acids.

Poly(2-hydroxyethylmethacrylate, HEMA)는 contact lens 재료물질로 사용되고, 물을 약 45퍼센트 포함하여 수화겔(hydrogel)을 만들 수 있는 고분자이다. Poly(HEMA)와 아미노산(alanine, arginine, methionine, proline, glycine, serine, lysine)과의 상호작용력을 DSC와 TGA 열분석법으로 측정한 결과 lysine, arginine, alanine의 결합성이 큼을 알 수 있었다.

Keywords

References

  1. Nature v.185 Wichterle, O.;Lim, D.
  2. U. S. Patent 2,976,576 Wichterle, O.;Lim, D.
  3. ACS Symposium Series 31 Hydrogels for Medical and Related Applications Ratner, B. D.;Hoffman, A. S.;Andrade, J. D.(ed.)
  4. J. Biomed. Mater. Res. v.9 Murray, D. G.
  5. J. Miomed. Mater. Res. v.3 Tollar, M.;Stol, M.
  6. Trans. Amer. Soc. Artif. Int. Organs v.XXII Nathan, P.;Law, E. J.;MacMillan, B. G.;Murphy, D. F.
  7. Trans. Amer. Soc. Artif. Int. Organs v.XIV Levowitz, B. S.;LaGuerre, J. N.;Calem, W. S.;Gould, F. E.;Scherer, J.;Schoenfeld, H.
  8. J. Biomed. Mater. Res. v.7 Spacek, P.;Kubin, M.
  9. J. Biomed. Mater. Res. v.3 Fefojo, M. F.
  10. Survey of Opthamology v.16 Refojo, M. F.
  11. Polymer v.3 Fox, T. G.;Schnecko, H. W.
  12. J. Polymer Sci. v.46 Good, W. E.;Owens, F. H.;Fellman, R. P.;Snyder, W. H.;More, J. E.
  13. A. Quart. Rev. (London) v.16 Bown, C. E. H.;Ledwith, A.
  14. J. Polymer Sci. v.31 Fox, T. G.;Goode, W. E.;Gratch, S.;Huggett, C. M.;Kincaid, J. F.;Spell, A.;Stroupe, J. D.
  15. ACS Symposium Series 31 Hydrogels for Medical and Related Applications Andrade, J. D.
  16. J. Biomed. Mater. Res. v.7 Jhon, M. S.;Andrade, J. D.
  17. Polym. Prepr. Amer. Chem. Soc. Div. Polym. Chem. v.15 Lee, H. B.;Andrade, J. D.;Jhon, M. S.
  18. J. of Colloid and Interface Science v.5 no.2 Lee, H. B.;Jhon, M. S.;Andrade, J. D.
  19. CRC Handbook of Chemistry and Physics(67th Edn.) Weast, R. C.(ed.);Astle, M. C.(ed.);Beyer, W. H.(ed.)
  20. CRC Hnadbook of Chemistry and Physics(67th Edn.) Weast, R. C.(ed.);Astle, M. C.(ed.);Beyer, W. H.(ed.)
  21. J. of Plymer Science Part A-1 v.10 Ratner, B. D.;Miller, I. F.