Biotechnology and Bioprocess Engineering:BBE

The Korean Society for Biotechnology and Bioengineering (한국생물공학회)
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Production of cis, cis-Muconic Acid from Benzoic Acid via Microbial Transformation

  • SangGu Bang (Interdisciplinary Program in Biochemical Engineering and Biotechnology Major) ;
  • Won (Department of Chemical Technology, College of Engineering, Seoul National University Department of Chemical Technology, College of Engineering, Seoul National University Department of Chemical Engineering, Youngnam University)
  • Published : 1996.12.01
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Abstract

For the production of cis, cis-muconic acid via biocatalytic conversion reactions from a toxic cosubstrate, benzoic acid, a fed-batch process using computer-controlled DO-stat feeding was developed. The mutant strain of Pseudomonas putida BM014 produced cis, cis-muconic acid from benzoic acid with high conversion yield. More than 32 g/L of cis, cis-muconic acid was accumulated in 42h and a productivity of 1.4g/(L.h)was achieved.

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