생체조직내에서 반사광을 이용한 확산 상수의 측정에 관한 연구

A Study on Diffusion Constant Measurement Using Light Reflectance within Biological Tissue

  • 임현수 (충남대학교 의과대학 의공학 교실)
  • 발행 : 1996.06.01

초록

This paper is the study of the diffusion constant in order to calculate the percent oxygenation and percent blood volume using reflectance light within biological tissue. The diffusion constant play major role in percent oxygenation and percent blood volume and varies with the biological material such as hemolyzed blood, whole blood, dermis and epidermis in vivo tissue. The diffusion constant can be modeled to consist of a contribution from bloodless tissue and blood present in tissue. The reflectance light for experimental are red light of 660nm, infrared light of 880nm, green light of 569nm. The correlation between the diffusion constant and biological tissue was analyzed by the intensity of reflectance light at different depth within human limb. The reflectance light was changed in response to physiological changes within biological tissue. The data for diffusion constant were obtained at different depth beneath the surface of the skin and will be utilized to amen the percent oxygenation and percent blood volume.

키워드

참고문헌

  1. Wave Propapagation and Scattering in Random Media A. Ishimaru
  2. IEEE Trans. on Biomedical Engineering v.39 The relationship of surface reflectance measurements to optical properties of layered biological media W. Cui;L.E. Ostrander
  3. Journal of Clinical Engineering v.18 Skin Blood Flow Measurements-A review of noninvasive Methodes R.S, Abdul;D. Bukhari;P.E, Sc
  4. IEEE Trans. Biomed. Eng. v.35 Noninvasive pulse oximetry utilizing skin reflectanc photoplethysmography Y. Mendelson;B.D, Ochs
  5. Contemporary Oethopaedics v.13 no.3 Use of cutaneous pressure photoplethysmography in managing peripheral vascular occlusive disease : preliminary report B.Y Lee;L.E. Ostrander
  6. Ph. D dissertation, Dept. Bio. Eng., Rensselaer Polytechic Institute Photon diffusion theory and noninvasive tissue optical measurement W. Cui;L.E. Ostrander
  7. Br.J Plast.Surg. v.29 The photoelectric plethysmography monitor of microvascular anastomoses MHC. Webster;J. Patterson
  8. 의공학회지 v.15 no.3 光 擴散經路 모델을 이용한 皮庸組織에서의 光 特性에 關한 硏究 임현수
  9. 의공학회지 v.14 no.1 加熱과 運動에 희한 生體組稷의 生理的 變化에 따른 光學的 特性의 變化에 관한 硏究 임현수;허웅
  10. Northeast Bioengineering Conference Effect of exercise on in vivo reflectance from the skin surface H.S Lim;L.E Ostrander
  11. IEEE Biomedical Engineering Conference Skin surface light reflectance : effects of exercise H.S Lim;L.E Ostrander
  12. Surg, Gynecol, Obstet. v.148 Assessment of the healing potentials of ulcers of the skin by photoplethysmography B.Y, Lee;F.S, Traubir;D. Kaver;J.A, Crislolgo;W.W. Shaw;J.L, Madden
  13. Surgery v.86 The use of Photoplethysmography in the assessment of venous insufficiency : A comparison of venous pressure measurements H.B, Abramowitz;L.A. Queral;W.R. Flinn;PF, Nora;LK, Peterson;JJ, Bergan;Yoa JST
  14. Br. J. Plast. Surg. v.21 The measurement of blood flow by a photoelectric technique and its application to the management of tubed skin pedicles I.F.K;Muir(et al.)
  15. IEEE Trans. Biomed. Eng. v.35 Noninvasive pulse oximetry utilizing skin reflectanc photoplethysmography Y. Mendelson;B.D, Ochs
  16. Nature Functional architecture of cortex revealed by optical imaging of intrinsec signals A. Grinwald;E. Lieke;R.D. Frostig;C.D. Gilbert;T.N. Wiesel
  17. Acta Radiol. optical spertros-copy : pre-mammography marker R. L. Egan;P. D. Dolan
  18. Pro. SPIC An optical fiber-based diffuse reflectance spectrometer for non-invasive investigation of photodynamic sensitizer in vivo B. C. wilson;T. J Farrell;M. S. Patterson
  19. Phys. Med. Biol. Aspects of laser light scattering from skin tissue with application to laser Doppler blood flow measurement R. J. Gush;T. A. King;M. I. V. Jayson