Parasites, Hosts and Diseases
- 제34권3호
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- Pages.211-213
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- 1996
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- 2982-5164(pISSN)
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- 1738-0006(eISSN)
Electrophoretic variations of enzyme, GDH (NADP-dependent glutamate dehydrogenase)(EC. 1.4.1.4) in characterizing clones and isolates of Malaysian Plasmodium falciparum
- Ang, Hooi-Hoon (School of Pharmaceutical Sciences, University of Science Malaysia) ;
- Chan, Kit-Lam (School of Pharmaceutical Sciences, University of Science Malaysia) ;
- Mak, Joon-Wah (Malaria Division, Institute for Medical Research)
- 발행 : 1996.09.01
초록
Malaysian, Ajricn and Thai PZQsmodiumJnkipamm isolates were cultured in uiko by the Tracer and Jensen method (1976, 1977) and were later cloned by the limiting dilution method (Rosario, 1981), Forty-eight clones were obtained and were characterized by electrophoretic variations of GDH (NADP-dependent glutamate dehydrogenase)(EC. 1.4.1.4). It was found that they were pure clones because they possessed either GDH-1 or GDH-2 unlike their parent isolates which exhibited both GDH-1 and GDH-2.
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