Korean Journal of Oriental Medicine (한국한의학연구원논문집)
- Volume 2 Issue 1
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- Pages.205-225
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- 1996
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- 1229-3377(pISSN)
The effect of Youngyanggaksan on the anticonvulsive, antipyretic, analgesic, sedative and GABAergic system
영양각산(羚羊角散)이 진경(鎭痙), 해열(解熱), 진통(鎭痛), 진정(鎭靜) 및 GABAergic system에 미치는 영향
- Kim, Jin-Hee (Department of Internal Medicine, College of Oriental Medicine, Wonkang University) ;
- Moon, Byoung-Soon (Department of Internal Medicine, College of Oriental Medicine, Wonkang University) ;
- Sung, Kang-Kyoung (Department of Internal Medicine, College of Oriental Medicine, Wonkang University)
- Published : 1996.12.30
Abstract
This study has been carried out to investigate the effects of Youngyanggaksan (YGS) extract on the anticonvulsive, antipyretic, anlgesic, sedative and GABAergic system of experimental animals. The results of this study were as follows : 1. YGS extract prolonged significantly the beginning time to convulsion and time to death induced by strychnine. 2. YGS extract prolonged significantly the time to death induced by electrical shock of ECT unit (3sec, 200F, 25mA). 3. On the experiment of hypothermic effects of YGS extract on the rectal temperature of rats, YGS extract decreased significantly the rectal temperature of rats. 4. On the experiment of antipyretic effects of YGS extract on the febrile induced by the subcutaneous injection of