Korean Journal of Pharmacognosy (생약학회지)
- Volume 27 Issue 1
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- Pages.53-57
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- 1996
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- 0253-3073(pISSN)
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- 2288-9299(eISSN)
Anticonvulsant Effect of Uncariae Ramulus et Uncus. I. -Anticonvulsant Effect of Ethyl Acetate Fraction-
조구등(釣鉤藤) 성분의 항경련 효과 I. -에틸아세테이트 분획의 항경련 효과-
- Kim, Dong-Young (College of Pharmacy, Kyungsung University) ;
- Kim, Hoe-Young (College of Pharmacy, Kyungsung University) ;
- Park, Min-Soo (College of Pharmacy, Kyungsung University) ;
- Lee, chung-Gyu (College of Pharmacy, Kyungsung University) ;
- Choi, Jong-Won (College of Pharmacy, Kyungsung University)
- Published : 1996.03.30
Abstract
To elucidate the activities of Uncaria Ramulus et Uncus, which has been used as anticonvulsant and antihypertensive in oriental region, the methanolic extract and its fractions were applied to inhibition of convulsion onset. The ethyl acetate fraction showed dose-dependent inhibitory activity against pentylenetetrazole-induced seizure.